LSD1-IN-46 is a potent and orally active Lysine-specific demethylase 1 ( LSD1 ) inhibitor with an IC 50 of 0.082 μM. LSD1-IN-46 interrupts the β-catenin-mediated transcriptional program, thereby suppressing the stemness of gastric cancer cells. LSD1-IN-46 exhibits strong anti-tumor activity. LSD1-IN-46 can be used for the research of gastric cancer .
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