LDN-193688

Overview

LDN-193688 (Compound 26) is a ALK2 inhibitor, with IC₅₀ values of 104, 18, 235, 1530, and 1080 nM against ALK1 , ALK2 , ALK3 , ALK4 , and ALK5 , respectively. LDN-193688 inhibits bone morphogenetic protein 4 (BMP4)-induced phosphorylation of SMAD1/5/8 , with an IC₅₀ of 2.6 μM.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Others | Products > Signaling Pathways > Anaplastic lymphoma kinase (ALK) | Products > Signaling Pathways > TGF-beta/Smad

Product Information

• Catalog No.: HY-179400
• CAS No.: 1062368-51-7
• Molecular Formula: C22H16N4O
• Molecular Weight: 352.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source