NSD2-PWWP1-IN-5

Overview

NSD2-PWWP1-IN-5 (Compound 13) is an effective NSD2-PWWP1 inhibitor with a K d value of 78 nM. NSD2-PWWP1-IN-5 competitively blocks the recognition of H3K36me2 and DNA by NSD2-PWWP1, thereby weakening its binding ability to nucleosomes. NSD2-PWWP1-IN-5 inhibits the proliferation of U2OS osteosarcoma cells and induces cell cycle arrest and apoptosis . NSD2-PWWP1-IN-5 can be used for the study of osteosarcoma.

Application

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Product Information

• Catalog No.: HY-179650
• CAS No.: 217798-45-3
• Molecular Formula: C13H10N2OSe
• Molecular Weight: 289.19
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source