PCI 29732

Overview

PCI 29732 is a potent, orally active, reversible BTK inhibitor with K i app values of 8.2, 4.6, and 2.5 nM for BTK , Lck and Lyn , respectively. PCI 29732 shows only modest inhibitory activity against Itk , another Tec family kinase. PCI 29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2.

Application

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Product Information

• Catalog No.: HY-18010
• CAS No.: 330786-25-9
• Molecular Formula: C22H21N5O
• Molecular Weight: 371.44
• Purity: 99.59%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1 mg/mL (2.69 mM); Clear solution
• Availability: In-stock

Source

Original product source