EGFR/BRAFV600E-IN-6

Overview

EGFR/BRAFV600E-IN-6 (Compound 7c) is a dual EGFR/BRAF V600E inhibitor with IC 50 values of 0.12 and 0.05 μM. EGFR/BRAFV600E-IN-6 can activate caspase-3/8/9 , unregulate Bax expression and downregulate Bcl-2 levels. EGFR/BRAFV600E-IN-6 can induce apoptosis and shows antioxidant activity. EGFR/BRAFV600E-IN-6 can be used for the research of cancer , such as colon cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > EGFR/VEGFR Mutation Colorectal Cancer | Products > Disease Areas > BRAF Mutation Colorectal Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Raf | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-180154
• CAS No.: 3120155-78-1
• Molecular Formula: C28H21N5O3S
• Molecular Weight: 507.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source