IAG-10

Overview

IAG-10 is a selective DNA polymerase kappa ( hpol κ ) inhibitor with an IC 50 value of 7.2 μM. IAG-10 exerts its function by disrupting the formation of the binary complex between the enzyme and DNA. IAG-10 enhances the antiproliferative and DNA-damaging activities of Temozolomide ( HY-17364 ) in tumor cells with functional hpol κ expression. IAG-10 can be used in the research of cancers such as malignant brain tumors.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-180392
• CAS No.: 2361305-69-1
• Molecular Formula: C21H17Cl2N5O
• Molecular Weight: 426.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source