Solimastat

Overview

Solimastat (BB-3644) is a potent metalloproteinase ( MMP ) inhibitor that blocks constitutive and antibody-stimulated CD30 shedding from cell surfaces with an IC 50 of 180 nM. Solimastat enhances persistence of anti-CD30 antibody Ki-3 on cells and favors its internalization. Solimastat enhances cytotoxic activity of Ki-3.dgA towards CD30 + L540 cells. Solimastat can be used for the research of CD30 + malignancies.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-180412
• CAS No.: 226072-63-5
• Molecular Formula: C20H32N4O5
• Molecular Weight: 408.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source