SMU-C409

Overview

SMU-C409 is a TLR1/2 agonist with an EC 50 of 65 nM in HEK-Blue hTLR2 Cells. SMU-C409 activates the TLR1/2 – MyD88 – NF-κB pathway, inducing TNF-α / IL-1β secretion and robust immune cell activation for antitumor immunomodulation. SMU-C409 shows low toxicity in virto. SMU-C409 can be used for cancer immunotherapy research.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer Immunology | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > MyD88 | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-180580
• CAS No.: 3113739-61-7
• Molecular Formula: C21H21N3OS2
• Molecular Weight: 395.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source