PRE-084 hydrochloride

PRE-084 hydrochloride
  • CAS No.:75136-54-8
  • Grade:99.92%
  • Formula:C19H28ClNO3
  • M.W.:353.88
  • Solvent:≥ 2.08 mg/mL (5.88 mM); Clear solution

Overview

PRE-084 hydrochloride is a highly selective σ1 receptor ( S1R ) agonist, with an IC 50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Sigma Receptor | Products > Signaling Pathways > Akt | Products > Signaling Pathways > NO Synthase

Product Information

  • Catalog No.: HY-18100A
  • CAS No.: 75136-54-8
  • Molecular Formula: C19H28ClNO3
  • Molecular Weight: 353.88
  • Purity: 99.92%
  • Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
  • Solubility: ≥ 2.08 mg/mL (5.88 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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