TIPARP-IN-1

Overview

TIPARP-IN-1 (Compound 15) is a selective PARP7 ( TIPARP ) (2,3,7,8-Tetrachlorodiben-zo-p-dioxin(TCDD)-inducible PARP ) inhibitor with an IC 50 of 2.15 nM. TIPARP-IN-1 can restore IFN signaling pathway in tumors by inhibiting TIPARP. TIPARP-IN-1 selectively activates the anti-tumor immune response in the tumor microenvironment and avoids the production of systemic cytokines. TIPARP-IN-1 can be used for research of head and neck squamous cell carcinoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Melanoma | Products > Disease Areas > Squamous Cell Carcinoma | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PARP | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-181027
• CAS No.: 3106183-96-1
• Molecular Formula: C22H23F6N5O2
• Molecular Weight: 503.44
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source