PDI-IN-5

Overview

PDI-IN-5 (compound 30z) is an allosteric-covalent inhibitor targeting protein disulfide isomerase ( PDI ) with a 2-chloro-pyrrolopyrimidin-4-one scaffold, with an IC 50 of 0.4 μM. PDI-IN-5 exhibits selectivity for ERp57 and GPX4 , and inhibits glioblastoma. PDI-IN-5 can be used in glioblastoma-related research.

Application

Products | Products > Disease Areas > Glioma | Products > Disease Areas > Glioblastoma | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > CNS Neoplasm | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PDI | Products > Signaling Pathways > Glutathione Peroxidase

Product Information

• Catalog No.: HY-181574
• CAS No.: 3097563-91-9
• Molecular Formula: C19H16Cl2N4O2
• Molecular Weight: 403.26
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source