HDAC6-IN-75 is a selective HDAC6 inhibitor with an IC 50 of 0.17 nM against HDAC6 . HDAC6-IN-75 induces the accumulation of acetylated α-tubulin in glioma cells. HDAC6-IN-75 triggers cell cycle changes, increases the SubG1 cell population, and promotes apoptosis in glioma cells and glioblastoma stem cells. HDAC6-IN-75 is applicable for glioma-related research.
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