TPKI-39 is a DDR1 , DDR2 , and FLT1 inhibitor, with a human DDR1 IC 50 of 380 nM, human DDR1 K a of 24 nM, human DDR2 IC 50 of 120 nM, human FLT1 IC 50 of 65 nM, and human FLT1 K a of 91 nM.TPKI-39 inhibits DDR1 enzymatic activity and autophosphorylation, DDR2 enzymatic activity, and FLT1 enzymatic activity in cells.TPKI-39 inhibits collagen-induced DDR1 autophosphorylation in cells.
Products | Products > Disease Areas > Others | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Others | Products > Signaling Pathways > Discoidin Domain Receptor
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