Ki 23057

Overview

Ki 23057 is a competitive, orally active inhibitor for tyrosine kinase , which inhibits the phosphorylation of K-samII/FGF-R2 , VEGF-R1, VEGF-R2, PDGF-Rβ and c-Kit , with IC 50 s of 88, 69, 83, 100 and 480 nM. Ki 23057 inhibits the proliferation of sclerogastric cancer cells OCUM-2MD3 and OCUM-8, and induces apoptosis . Ki 23057 exhibits antitumor efficacy in mouse models.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-18187
• CAS No.: 516523-31-2
• Molecular Formula: C30H35N3O4
• Molecular Weight: 501.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source