OP-3136

Overview

OP-3136 is an orally active, highly selective inhibitor of KAT6A and KAT6B . OP-3136 inhibits the proliferation of prostate cancer , ovarian cancer and non-small cell lung cancer cells that express or overexpress KAT6A . OP-3136 reduces the proliferative capacity of cancer cells and suppresses cell growth in ER + breast cancer cell models with KAT6 overexpression. OP-3136 induces tumor regression and inhibits tumor growth in an ovarian cancer xenograft model in immunodeficient mice. OP-3136 inhibits tumor growth in a non-small cell lung cancer xenograft model in immunodeficient mice. OP-3136 can be used in research related to HR + /HER 2- breast cancer , prostate cancer , ovarian cancer and non-small cell lung cancer (NSCLC).

Application

Products | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Luminal Breast Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Acetyltransferase

Product Information

• Catalog No.: HY-182468
• CAS No.: 3056105-63-3
• Molecular Formula: C20H22N4O7S
• Molecular Weight: 462.48
• Purity: 99.90%
• Storage: -80°C
• Availability: In-stock

Source

Original product source