SYN1143

Overview

SYN1143 is a potent, selective and orally active dual inhibitor of c-Met/RON , with IC 50 s of 4 and 9 nM, respectively. SYN1143 has weak inhibitory activity on Lck , Tie2 , Src , and BTK with IC 50 s ranging from 160 to 710 nM. SYN1143 can be used for the research of cancers that RON and c-Met are activated.

Application

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Product Information

• Catalog No.: HY-18307
• CAS No.: 913376-84-8
• Molecular Formula: C31H29FN4O5
• Molecular Weight: 556.58
• Purity: 99.07%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (4.49 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source