Takeda-6D

Overview

Takeda-6D (compound 6d) is an orally active and potent BRAF/VEGFR2 inhibitor, with IC 50 values of 7.0 and 2.2 nM, respectively. Takeda-6D shows antiangiogenesis by suppressing the VEGFR2 pathway in 293/KDR and VEGF-stimulated HUVEC cells.Takeda-6D shows significant suppression of ERK1/2 phosphorylation. Takeda-6D shows antitumor activity.

Application

Products | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Raf | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > PERK

Product Information

• Catalog No.: HY-18318
• CAS No.: 1125632-93-0
• Molecular Formula: C27H19ClFN5O3S
• Molecular Weight: 547.99
• Purity: 99.41%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source