1400W Dihydrochloride

Overview

1400W dihydrochloride is the dihydrochloride form of 1400W ( HY-18730 ). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase ( iNOS ) inhibitor, with a K d value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation.

Application

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Product Information

• Catalog No.: HY-18731
• CAS No.: 214358-33-5
• Molecular Formula: C10H17Cl2N3
• Molecular Weight: 250.17
• Purity: 99.94%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2 mg/mL (7.99 mM); Clear solution
• Availability: In-stock

Source

Original product source