L-NMMA (Tilarginine) is a non-selective and competitive inhibitor of nitric oxide synthase . L-NMMA inhibits three subtypes, namely nNOS , eNOS , and iNOS , and reduces NO production . L-NMMA alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA is applicable to research related to nociception, bone cancer pain, and myopia.
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