TG 100801 Hydrochloride

Overview

TG 100801 Hydrochloride is a proagent that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases ; has IC 50 s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ , Fgr, Fyn , Hck , Lck , Lyn , Src , Yes , respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > FGFR | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > Src

Product Information

• Catalog No.: HY-10187
• CAS No.: 1018069-81-2
• Molecular Formula: C33H31Cl2N5O3
• Molecular Weight: 616.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source