AMI-1 free acid

Overview

AMI-1 free acid is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs) , with IC 50 s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 free acid exerts PRMTs inhibitory effects by blocking peptide-substrate binding.

Application

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Product Information

• Catalog No.: HY-18962A
• CAS No.: 134-47-4
• Molecular Formula: C21H16N2O9S2
• Molecular Weight: 504.49
• Purity: 99.53%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.12 mM); Clear solution
• Availability: In-stock

Source

Original product source