SAR405838

Overview

SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a K i of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53 | Products > Signaling Pathways > E1/E2/E3 Enzyme | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-18986
• CAS No.: 1303607-60-4
• Molecular Formula: C29H34Cl2FN3O3
• Molecular Weight: 562.50
• Purity: 98.84%
• Storage: -20°C, sealed storage, away from moisture * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 2.5 mg/mL (4.44 mM); Clear solution
• Availability: In-stock

Source

Original product source