GSK180736A

Overview

GSK180736A is potent Rho-associated coiled-coil kinase 1 ( ROCK1 ) inhibitor with an IC 50 of 100 nM. GSK180736A is also a selective and ATP-competitive G protein-coupled receptor kinase 2 (GRK2) inhibitor with an IC 50 of 0.77 μM.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > ROCK | Products > Signaling Pathways > G Protein-coupled Receptor Kinase (GRK)

Product Information

• Catalog No.: HY-18990
• CAS No.: 817194-38-0
• Molecular Formula: C19H16FN5O2
• Molecular Weight: 365.36
• Purity: 98.81%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.84 mM); Clear solution
• Availability: In-stock

Source

Original product source