TMS ((E)-2,3',4,5'-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC 50 of 6 nM and a K i value of 3 nM. TMS shows a lesser extent inhibitory effect on CYP1A1 (IC 50 =300 nM) and CYP1A2 (IC 50 =3.1 μM). TMS is a methylated derivative of resveratrol and has anti-cancer activity.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Cytochrome P450
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