Pimelic Diphenylamide 106

Overview

Pimelic Diphenylamide 106 (TC-H 106) is a slow, tight binding class I HDAC inhibitor (inhibits HDAC1 , 2, and 3 with IC 50 values of 150 nM, 760 nM, and 370 nM, respectively), with no activity against class II HDACs . Pimelic Diphenylamide 106 modulates dopamine concentration and protects dopamine cells by inducing VMAT2 expression. Pimelic Diphenylamide 106 can be used in the study of neuropsychiatric diseases such as attention deficit hyperactivity disorder (ADHD).

Application

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Product Information

• Catalog No.: HY-19348
• CAS No.: 937039-45-7
• Molecular Formula: C20H25N3O2
• Molecular Weight: 339.43
• Purity: 98.54%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 0.55 mg/mL (1.62 mM); Clear solution
• Availability: In-stock

Source

Original product source