NSC-658497

Overview

NSC-658497 is an effective inhibitor of Ras-GEF, SOS1 . NSC-658497 binds to SOS1, competitively suppresses SOS1-Ras interaction, and dose-dependently inhibits SOS1 GEF activity. NSC-658497 showed dose-dependent efficacy in inhibiting Ras , downstream signaling activities, and associated cell proliferation.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > SOS1 | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-19539
• CAS No.: 909197-38-2
• Molecular Formula: C20H10N2O6S2
• Molecular Weight: 438.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source