Brusatol

Overview

Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent. Brusatol increases cellular apoptosis .

Application

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Product Information

• Catalog No.: HY-19543
• CAS No.: 14907-98-3
• Molecular Formula: C26H32O11
• Molecular Weight: 520.53
• Purity: 99.94%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 1 year; -20°C, 6 months (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (4.80 mM); Clear solution
• Availability: In-stock

Source

Original product source