JX06

Overview

JX06 is a potent, selective and covalent inhibitor of PDK . JX06 inhibits PDK1 , PDK2 and PDK3 with IC 50 s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PDHK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-19564
• CAS No.: 729-46-4
• Molecular Formula: C10H16N2O2S4
• Molecular Weight: 324.51
• Purity: 99.78%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.70 mM); Clear solution
• Availability: In-stock

Source

Original product source