SRT 2183

Overview

SRT 2183 is a selective Sirtuin-1 ( SIRT1 ) activator with an EC 1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis , concomitant with deacetylation of STAT3 and NF-κB , and reduction of c-Myc protein levels.

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Obesity | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Sirtuin | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-19759
• CAS No.: 1001908-89-9
• Molecular Formula: C27H24N4O2S
• Molecular Weight: 468.57
• Purity: 98.06%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.44 mM); Clear solution
• Availability: In-stock

Source

Original product source