VX-984

Overview

VX-984 is an orally active, potent, selective and BBB-penetrated DNA-PK inhibitor . VX-984 efficiently inhibits NHEJ (non-homologous end joining) and increases DSBs (DNA double-strand breaks). VX-984 can be used for glioblastomas (GBM) and non-small cell lung cancer (NSCLC) research. VX-984 is a de novo deuterium.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA-PK

Product Information

• Catalog No.: HY-19939S
• CAS No.: 1476074-39-1
• Molecular Formula: C23H21D2N7O
• Molecular Weight: 415.49
• Purity: 99.47%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1 mg/mL (2.41 mM); Clear solution
• Availability: In-stock

Source

Original product source