Derazantinib dihydrochloride

Overview

Derazantinib (ARQ-087) dihydrochloride is an ATP competitive and orally active FGFR inhibitor ( IC 50 s: 1.8 nM for FGFR2, 4.5 nM for FGFR1 and 3). Derazantinib dihydrochloride inhibits FGFR phosphorylation. Derazantinib dihydrochloride inhibits tumor growth in multiple xenograft models.

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-19981B
• CAS No.: 1821329-75-2
• Molecular Formula: C29H31Cl2FN4O
• Molecular Weight: 541.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source