Selitrectinib

Overview

Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC 50 s of 0.6 nM and <2.5 nM for TRKA and TRKC , respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Pain | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Trk Receptor

Product Information

• Catalog No.: HY-101977
• CAS No.: 2097002-61-2
• Molecular Formula: C20H21FN6O
• Molecular Weight: 380.42
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (5.47 mM); Clear solution
• Availability: In-stock

Source

Original product source