EM20-25

Overview

EM20-25 is an inhibitor for Bcl-2 , which interferes with the interaction between BCL-2 and BAX , activates caspase-9 and thus induces the apoptosis . EM20-25 affects the mitochondrial function, causes the open of permeability transition pore (PTP). EM20-25 enhances the sensitivity of cells to Staurosporine ( HY-15141 ), and enhances the killing effect of BCL-2-expressing leukemia cells to Chlorambucil ( HY-13593 ) and Fludarabine ( HY-B0069 ).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-101999
• CAS No.: 141266-44-6
• Molecular Formula: C15H9ClN4O6
• Molecular Weight: 376.71
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source