7-Coumaryl triflate is a type 17β-HSD1 inhibitor of 17β-hydroxysteroid dehydrogenase. Its IC 50 is 360 nM and K i is 173 nM. 7-Coumaryl triflate shows selectivity for 17β-HSD2 and has no detectable affinity for ERα or ERβ . 7-Coumaryl triflate can be used in related research on hormone-dependent breast cancer .
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