A-769662

Overview

A-769662 is a AMP-activated protein kinase ( AMPK ) activator. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK ( EC 50 = 0.8 μM) and inhibits fatty acid synthesis in primary rat hepatocytes ( IC 50 = 3.2 μM). A-769662 can alleviate the symptoms of metabolic diseases such as type 2 diabetes.

Application

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Product Information

• Catalog No.: HY-50662
• CAS No.: 844499-71-4
• Molecular Formula: C20H12N2O3S
• Molecular Weight: 360.39
• Purity: 99.33%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.94 mM); Clear solution
• Availability: In-stock

Source

Original product source