Belotecan hydrochloride

Overview

Belotecan hydrochloride is a topoisomerase I inhibitor. It is a synthetic and water-soluble camptothecin derivative which forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. CKD-602 has a significant effect on intracerebral glioma growth, with animals having significantly smaller tumors than those in the control group.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | Topoisomerase

Product Information

• Catalog No.: B0084-087456
• CAS No.: 213819-48-8
• Molecular Formula: C25H27N3O4.HCl
• Molecular Weight: 469.96
• Purity: ≥98% by HPLC
• Storage: Store at 2-8 °C, under inert gas (nitrogen or Argon)
• Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)

Source

Original product source