PLX-4720

Overview

PLX-4720 is a potent and selective inhibitor of B-Raf V600E with IC 50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-Raf V600E than wild-type B-Raf .

Application

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Product Information

• Catalog No.: HY-51424
• CAS No.: 918505-84-7
• Molecular Formula: C17H14ClF2N3O3S
• Molecular Weight: 413.83
• Purity: 99.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (5.03 mM); Clear solution
• Availability: In-stock

Source

Original product source