TG53 is a potent inhibitor of tissue transglutaminase ( TG2 ) and fibronectin ( FN ) protein-protein interaction. TG53 inhibits formation of a complex with integrin β1 and activation of FAK and c-Src during SKOV3 cell attachment onto FN. TG53 can be used for ovarian cancer research.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Glutaminase | Products > Signaling Pathways > Integrin | Products > Signaling Pathways > FAK | Products > Signaling Pathways > Src
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