BMX-IN-1

Overview

BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys 496 in the BMX ATP binding domain with an IC 50 of 8 nM, also targets the related Bruton’s tyrosine kinase ( BTK ) with an IC 50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk , JAK3 , EGFR , Itk , or Tec activity.

Application

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Product Information

• Catalog No.: HY-80002
• CAS No.: 1431525-23-3
• Molecular Formula: C29H24N4O4S
• Molecular Weight: 524.59
• Purity: 98.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 10 mg/mL (19.06 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source