Ticlopidine hydrochloride

Overview

Ticlopidine (PCR 5332) hydrochloride, an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC 50 of 81.7 μM. Ticlopidine hydrochloride blocks several NTPDase isoenzymes with IC 50 s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively. Ticlopidine hydrochloride is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine hydrochloride inhibits CYP2C9 and CYP3A4 with IC 50 s of 26.0 and 32.3 μM, respectively.

Application

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Product Information

• Catalog No.: HY-B0153A
• CAS No.: 53885-35-1
• Molecular Formula: C14H15Cl2NS
• Molecular Weight: 300.25
• Purity: 99.99%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (8.33 mM); Clear solution
• Availability: In-stock

Source

Original product source