Afatinib oxalate

Overview

Afatinib (BIBW 2992) oxalate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib oxalate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer .

Application

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Product Information

• Catalog No.: HY-10261D
• CAS No.: 1398312-64-5
• Molecular Formula: C26H27ClFN5O7
• Molecular Weight: 575.97
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source