Quizartinib

Overview

This active molecular also known as AC220 and AC010220, is developed as a new second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, ten fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Now Quizartinib is in Phase-III clinical trials in Acute myeloid leukaemia.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | FLT3

Product Information

• Catalog No.: B0084-157290
• CAS No.: 950769-58-1
• Molecular Formula: C29H32N6O4S
• Molecular Weight: 560.67
• Purity: 98%
• Storage: -20°C Freezer
• Solubility: Soluble in DMSO

Source

Original product source