Vardenafil hydrochloride

Overview

Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 ( PDE5 ), with an IC 50 of 0.7 nM. Vardenafil hydrochloride shows inhibitory towards PDE1 , PDE6 with IC 50 s of 180 nM, and 11 nM, while IC 50 s are >1000 nM for PDE3 and PDE4 . Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil hydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes [1]-[6] .

Application

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Product Information

• Catalog No.: HY-B0442A
• CAS No.: 224785-91-5
• Molecular Formula: C23H33ClN6O4S
• Molecular Weight: 525.06
• Purity: 99.79%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.76 mM); Clear solution
• Availability: In-stock

Source

Original product source