Celastrol

Overview

Celastrol (tripterine) is a novel Hsp90 inhibitor isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | HSP

Product Information

• Catalog No.: B0084-187070
• CAS No.: 34157-83-0
• Molecular Formula: C29H38O4
• Molecular Weight: 450.61
• Purity: >98%
• Storage: Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
• Solubility: Soluble in Chloroform (Slightly), Hexanes (Slightly, Heated), Methanol

Source

Original product source