Oxaprozin potassium

Overview

Oxaprozin potassium is an orally active and potent COX inhibitor, with IC 50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2 , respectively. Oxaprozin potassium also inhibits the activation of NF-κB . Oxaprozin potassium induces cell apoptosis . Oxaprozin potassium shows anti-inflammatory activity. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > COX | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Akt | Products > Signaling Pathways > IKK

Product Information

• Catalog No.: HY-B0808A
• CAS No.: 174064-08-5
• Molecular Formula: C18H14KNO3
• Molecular Weight: 331.41
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source