Dimesna

Overview

Dimesna (BNP-7787), the disulfide form of Mesna ( HY-13679 ), is a platinum-related toxicity protective agent. Dimesna converts to Mesna, which in turn inactivates toxic platinum substances. Dimesna does not interfere with the antitumor activity of platinum compounds. Dimesna does not affect the antiproliferative effects of Cisplatin ( HY-17394 ) or Carboplatin ( HY-17393 ). Dimesna counteracts Cisplatin -induced nephrotoxicity. Dimesna exerts selective protective effects on the kidneys. Dimesna can be used in studies related to ovarian cancer and Cisplatin -induced nephrotoxicity.

Application

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Product Information

• Catalog No.: HY-B1022
• CAS No.: 16208-51-8
• Molecular Formula: C4H8Na2O6S4
• Molecular Weight: 326.34
• Purity: 98.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source