Dimesna free acid

Overview

Dimesna (BNP-7787) free acid, the disulfide form of Mesna ( HY-13679 ), is a platinum-related toxicity protective agent. Dimesna free acid converts to Mesna, which in turn inactivates toxic platinum substances. Dimesna free acid does not interfere with the antitumor activity of platinum compounds. Dimesna free acid does not affect the antiproliferative effects of Cisplatin ( HY-17394 ) or Carboplatin ( HY-17393 ). Dimesna free acid counteracts Cisplatin -induced nephrotoxicity. Dimesna free acid exerts selective protective effects on the kidneys. Dimesna free acid can be used in studies related to ovarian cancer and Cisplatin -induced nephrotoxicity.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Renal Disease | Products > Signaling Pathways > Others | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Endocrinology | Products > Research Areas > Cancer | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-B1022A
• CAS No.: 45127-11-5
• Molecular Formula: C4H10O6S4
• Molecular Weight: 282.38
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source