Oxidopamine hydrochloride

Overview

Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine . Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE 2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrochloride can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Mitophagy | Products > Signaling Pathways > COX | Products > Signaling Pathways > PGE synthase | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Dopamine Receptor | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-B1081
• CAS No.: 28094-15-7
• Molecular Formula: C8H12ClNO3
• Molecular Weight: 205.64
• Purity: 98.97%
• Storage: 4°C, stored under nitrogen, away from moisture * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: 50 mg/mL (243.14 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source