SCH442416

Overview

SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A 2A receptor (A 2A R) , with K i s of 0.048 and 0.5 nM for human and rat A 2A R respectively. SCH442416 displays more than 23000-fold selectivity over A 1 R, A 2B R, and A 3 R (K i =1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A 2A receptors in rat and primate brain.

Application

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Product Information

• Catalog No.: HY-103169
• CAS No.: 316173-57-6
• Molecular Formula: C20H19N7O2
• Molecular Weight: 389.41
• Purity: 99.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 0.2 mg/mL (0.51 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source