Terfenadine

Overview

Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC 50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca 2+ homeostasis. Terfenadine induces ROS-dependent apoptosis , simultaneously activates Caspase-4, -2, -9 .

Application

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Product Information

• Catalog No.: HY-B1193
• CAS No.: 50679-08-8
• Molecular Formula: C32H41NO2
• Molecular Weight: 471.67
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.30 mM); Clear solution
• Availability: In-stock

Source

Original product source